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The best way to find High Level (40-50) Loot is at the Eridian Promontory during playthrough 2, as there are a number of weapon chests, the enemies are all level 50+ and there is alot of loot around.

Killing bosses during playthrough 2 is also a good idea.

If you haven't finished playthrough 2 yet, get a friend to take you gun harvesting in this area, prefrebly a level 50 friend.

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